St. Nino Church is one of the churches in Ortahisar town of Nevşehir province. It takes its name from Nino of Cappadocia, known as the saintess who spread Christianity in Georgia. The street where the church is located bears the name of St. Nino. St. Nino Church, which is a two-storey structure, was built by carving into a pyramid-like rock. The first floor is the place of worship; It is estimated that the second floor served as a shelter. The adjacent room is thought to have been added later. St. Nino Church is a structure with a free cross plan and a dome. Since the oval upper part of the dome in the center collapsed, it was later covered with wood. The entrance opening of the church is located on the south arm of the cross. However, it is estimated that this door was opened later. The church has a single apse in the form of a horseshoe. The murals of the St. Nino Church have survived to a large extent. On the dome of the church, St. Jesus and St. Mary is pictured praying between two archangels. On the western wall of the church, the archangel is depicted in large size, and on the northern wall, the Deisis scene is depicted, although it has survived to the present day. Of the two archangels depicted on the west wall, it is understood from the writings below that the right one is Raphael and the left one is Azrael.